West Midlands Ambulance Service were called at 1.46pm following a collision involving a pedestrian and a trailer, being towed by a vehicle, on Newhampton Road East in Wolverhampton.
Two ambulances, two paramedic officers and the Midlands Air Ambulance from Cosford with a MERIT trauma doctor and a critical care paramedic on board attended the scene.
A West Midlands Ambulance Service spokeswoman said: “On arrival, crews found the pedestrian, a man, with serious injuries.
He received advanced trauma care on scene and was conveyed to Queen Elizabeth Hospital Birmingham via land ambulance on blue lights and sirens for further emergency treatment.”